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NFL · 2026 · AI Picks

Detroit Lions

Betting picks, ATS record, and odds analysis for Detroit Lions. Updated daily.

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Detroit Lions Injury Report

Amon-Ra St. Brown

WR

Per Spotrac, $26 million of St. Brown's salary was converted into a signing bonus, which alone created $20.8 million in cap space to give the Lions more flexibility for the next two seasons. St. Brown has been one of the most productive receivers since being selected by the Lions in the fourth round of the 2021 NFL Draft, having logged 100-plus catches and 1,000-plus receiving yards in each of the last four years. He finished the 2025 regular season with 117 catches (on a career-high 172 targets) for 1,401 yards and 11 touchdowns across 17 games. He'll once again lead a Lions pass-catching group that also includes Jameson Williams, Isaac TeSlaa and Sam LaPorta.

Active

Mekhi Wingo

DT

Wingo upgraded from a limited participant in the Wednesday and Thursday sessions to full participation in Friday's practice. The defensive tackle has managed to recover from a groin injury just in time to suit up for a depth role with the Lions' defense in Sunday's contest.

Active

Christian Izien

S

Izien has dealt with a groin injury throughout Week 1, logging limited participation in three consecutive practices. It is unclear how much the issue inhibits the reserve defensive back. If Izien must miss Sunday's contest, the Lions will likely elevate a defensive back from the practice squad to the active roster to fill in, as both Brian Branch (Achilles) and Kerby Joseph (knee) will miss the contest.

Questionable

Derrick Moore

DE

Moore was limited at practice earlier in the week with a hamstring issue, but he was able to log a full practice Friday and will be available in Week 1. Detroit used a second-round pick on the rookie back in April, so it wouldn't be surprising if he got significant playing time right away.

Active

Penei Sewell

OT

The Lions converted $18.6 million of Sewell's contract into a signing bonus to free up cap space. The team also restructured the contract of Amon-Ra St. Brown, pointing to a potential move for either a high-value player or increased depth sometime soon.

Active

Detroit Lions Pick History

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Detroit Lions Picks & Betting Analysis 2026

GODDS tracks every Detroit Lions bet with a public win-loss record. Our AI algorithm evaluates all Detroit Lions matchups using 18 signals — season record, ATS history, recent form, scoring edge, line movement, injuries, and head-to-head data.

The Detroit Lions play at Ford Field in Detroit, MI in the NFC North Division. Founded in 1930.

For upcoming Detroit Lions games, see Detroit Lions team page. For today's full slate, see NFL picks today.

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