Los Angeles Chargers

Brenen Thompson

WR

Thompson is dealing with a quad injury that already sidelined him for this past Sunday's loss to Buffalo. He's begun Week 4 prep with consecutive DNPs, so his chance of suiting up Sunday versus Seattle is looking quite grim. Prior to getting hurt, Thompson recorded one catch on three targets for 13 yards over his first two games.

Derwin James Jr.

S

Thursday's DNP represents a downgrade for James after he was a limited practice participant Wednesday. However, the Chargers' practice report lists the star safety as being sidelined due to both a hamstring injury and "rest," so it's unclear how serious the hamstring issue is. Los Angeles' practice report Friday should shed more light on James' chance of suiting up in Week 4.

Donte Jackson

CB

Jackson suffered a concussion in the team's 24-16 loss to the Bills in Week 3, and he was considered a non-participant at Wednesday's practice. His ability to return to practice Thursday is a step in the right direction, but he still has to clear concussion protocol before he'd be eligible to play Sunday versus Seattle.

Trey Lance

QB

Lance has been limited at each of the team's first two sessions of the week as he continues to nurse a groin issue. The quarterback was active for the team's loss to Buffalo in Week 3, and he'll likely be good to go Sunday versus the Seahawks.

Ladd McConkey

WR

McConkey showed up on the Chargers' first Week 4 injury report Wednesday as limited due to a foot injury. His downgrade to DNP one day later was potentially an ominous sign of things to come, and the aforementioned limp adds fuel to the fire that he may be in danger of sitting out Sunday's game at Seattle. Ultimately, the team may clarify McConkey's status when it posts its final practice report of the week Friday.

Alec Ingold

FB

Ingold hadn't received any touches in the first two games of the season, but he saw a surprising amount of involvement as an underneath target during the Week 3 loss. With snap shares of at least 38 percent in every game thus far, Ingold plays more frequently than the typical fullback, but he's utilized as a blocker first and foremost and can't be counted on to regularly contribute as a pass catcher.

Charlie Kolar

TE

Kolar hasn't practiced in any fashion since fracturing his left forearm in a Sept. 20 loss to the Raiders and undergoing surgery two days later. The Chargers have avoided placing Kolar on injured reserve with the expectation that he'll return to action within four games, but he'll almost certainly miss a second straight contest this Sunday in Seattle.

Keaton Mitchell

RB

For the second day in a row, Mitchell had his reps capped while he manages a left ankle injury. So long as he doesn't take a step back in activity during the Chargers' final practice of the week Friday, Mitchell should still be on track to suit up Sunday against the Seahawks. Through the team's first three games, Mitchell has carried 17 times for 85 yards (5.0 YPC) while adding four receptions for 10 yards and a touchdown in a complementary role behind lead back Omarion Hampton.

Tuli Tuipulotu

LB

Tuipulotu played 82 percent of the Chargers' defensive snaps in Sunday's loss. The outside linebacker sacked Josh Allen once and participated in another sack while the Chargers' defense notched five turnovers in a losing effort. The 24-year-old's 1.5 sacks were his first of the season after he notched a career-high 13.0 over 16 regular-season games in 2025.

Genesis Smith

S

Smith had a stellar defensive performance, picking off Josh Allen twice while the Chargers defense amassed five turnovers. Smith initially intercepted Allen at the Buffalo 43-yard line in the first quarter, and he followed it up with a bobbling grab at Los Angeles' 10-yard line during the second quarter. The free safety was starting due to the absence of Elijah Molden (hamstring), but Smith clearly held up well in coverage during the loss.

Justin Eboigbe

DT

questionable

Dalvin Tomlinson

DT

questionable

Elijah Molden

CB

questionable

Kayode Awosika

G

questionable

Oronde Gadsden

TE

With Charlie Kolar (forearm) and David Njoku (fibula, IR) both unavailable, Gadsden drew the start Sunday and led Los Angeles' tight ends with a 57 percent offensive snap share. However, Gadsden couldn't do anything with that workload, failing to reel in any of the three targets QB Justin Herbert tossed his way. Gadsden could have another chance to make an impact this coming Sunday against Seattle with both Kolar and Njoku set to remain sidelined, but the Seahawks have given up the third-fewest receiving yards to tight ends so far this season.

Quentin Johnston

WR

Johnston finished second on the team in targets, and his 40 receiving yards were nearly double his previous season total of 24 yards. He and the rest of the Chargers offense have yet to find their stride in 2026, making him hard to trust as a fantasy asset. The wide receiver will look to get back on track in a tough matchup in Week 4 against the Seahawks.

DJ Uiagalelei

QB

Alex Harkey

G

Tre' Harris

WR

Harris led the team in targets, receptions and receiving yards in the loss, all of which represented new career highs for the second-year pro. The wide receiver has now reeled in 10 of 16 targets for 149 yards over three games to open the regular season, and he appears to be on track to be a pivotal member of the team's passing attack in 2026.

Cameron Dicker

PK

Dicker's made field goals came from 33, 21 and 33 yards, with his miss early in the second quarter coming from 45 yards. Dicker has missed two of his five field-goal attempts through the first three games of the regular season, well below the 90 percent success rate he enjoyed in each of the first four years of his NFL career.

Justin Herbert

QB

Herbert finished with some serviceable numbers, but his play-to-play consistency lacked at times in a tough road environment. The 2020 first-round pick connected with a relatively narrow pool of six targets, and his one touchdown throw came via a shovel pass to Keaton Mitchell to cap off the opening drive of the game. Herbert also saw what was originally ruled a lost fumble returned for a touchdown reversed just before the two-minute warning, and through three games, he's completed only 59.1 percent of his passes while mustering a 3:4 TD:INT during an alarmingly winless start to the season for the Chargers. Herbert and his teammates draw a second straight unenviable assignment in Week 4, as they travel to face the defending champion Seahawks next Sunday afternoon.

Omarion Hampton

RB

The Chargers' No. 1 back got seven more carries than change-of-pace option Keaton Mitchell, but he was able to outpace the latter by only four yards. It was a disappointing downturn for Hampton, who'd broken out with 94 rushing yards and a touchdown while adding a 2-21-0 receiving line against the Raiders in Week 2. The Chargers are now alarmingly 0-3 heading into a daunting Week 4 road matchup against the Seahawks, but Hampton figures to remain in a clear-cut lead role for that contest.

Rodney Shelley

CB

Shelley was at risk of missing his first game of the season after sitting out practice Thursday, but he returned on a limited basis Friday and ended up getting cleared to play. The undrafted free agent has primarily served on special teams to start his career, and he did pick up his first two career tackles in Week 2 against the Raiders. He'll be slotted for a similar role this week in Buffalo.

Trey Pipkins III

OT

Pipkins suffered a knee injury sometime after Week 1 and has been unable to practice since. The offensive lineman will now need to miss four games on IR before becoming eligible to return to the Chargers' active roster.

Cole Strange

G