New England Patriots

Eli Raridon

TE

A thigh injury prevented the rookie third-rounder from playing against the Jaguars in Week 3. He was limited in all three practices prior to New England's loss to Jacksonville, so he may have to log a full practice over the next two days to have a realistic chance of playing Sunday against Buffalo.

Reggie Gilliam

FB

Gilliam was able to play in the Patriots' Week 3 loss to the Jaguars after working through a knee issue during practice prep. He played a total of 19 snaps (eight on offense, 11 on special teams) without showing up on the box score otherwise. Gilliam will have two more opportunities to log a full practice and avoid an injury designation for Sunday's AFC East tilt against the Bills.

Christian Gonzalez

CB

Gonzalez likely picked up the injury during the Patriots' 35-6 loss to the Jaguars in Week 3, when he recorded two solo tackles and a pass defense while failing to play every single defensive snap for the first time this season. He'll have two more chances to return to practice this week, but if he cannot play against the Bills this Sunday, then Charles Woods figures to be the top candidate to start at outside cornerback opposite Carlton Davis.

Christian Barmore

DT

Barmore sustained a shoulder injury during the Patriots' 35-6 loss to the Jaguars in Week 3, finishing with only two tackles (one solo) while playing a season-low 28 defensive snaps. He'll have two more chances to return to practice ahead of Sunday's game against the Bills. If Barmore is not cleared to play, then Joshua Farmer and Jeremiah Pharms would both be in line for larger roles against Buffalo.

Morgan Moses

OT

questionable

Christian Elliss

LB

questionable

Drake Maye

QB

Though he took every rep Wednesday and is on track to start Sunday's game in Buffalo, the lingering shoulder injury could at least partially explain Maye's rough start to the season. After finishing as the runner-up to the Rams' Matthew Stafford in MVP balloting in 2025, Maye has been an early disappointment for fantasy managers, completing 63.7 percent of his passes for 585 yards while posting a 1:6 TD:INT and losing a fumble through the Patriots' first three games. A road game against the undefeated Bills doesn't exactly represent a great bounce-back opportunity for Maye, who will face pressure from a Bills pass rush led by NFL sack leader Greg Rousseau.

DeMario Douglas

WR

Douglas played 60 percent of the Patriots' offensive snaps in the loss. The sole ball the wide receiver was able to haul in went for a 38-yard gain, marking quarterback Drake Maye's longest pass of the afternoon. Douglas continues to be a threat out of the slot for a struggling Patriots offense.

Greg Van Roten

G

Van Roten sustained a thigh injury during the Patriots' 35-6 loss to the Jaguars in Week 3. The injury is severe enough for him to miss at least the next four games, so the earliest he can return is for Week 8 against the Dolphins on Sunday, Nov. 1. With both Van Roten and Mike Onwenu (ankle) on IR, the Patriots will turn to either Ben Brown or Walter Rouse to serve as the starting right guard for Week 4 against the Bills, per Mike Reiss of ESPN.com.

Craig Woodson

S

questionable

Dre'Mont Jones

DE

questionable

Romeo Doubs

WR

Doubs finished second on the Patriots in both catches and receiving yards to Mack Hollins, the latter of whom finished with a 6-87-0 line on nine targets. Doubs and Hollins will continue to operate as Drake Maye's top targets in the absence of A.J. Brown (ankle), who will miss at least the next two weeks while on injured reserve. Doubs will take a 6-145-0 line on 11 targets into a Week 4 road matchup against Buffalo.

Hunter Henry

TE

The Patriots offense struggled as a whole Sunday, with Drake Maye completing 14 of 25 passes for 199 yards (8.0 YPA) and two interceptions. Even with A.J. Brown (ankle, IR) sidelined for the last two weeks, Henry has logged just four catches for 45 yards on seven targets, and he's well behind pace to match his 60-768-7 line (on 87 targets) across 17 regular-season games in 2025. Up next is a Week 4 road tilt against the Bills, whose defense held Chargers tight end Oronde Gadsden catchless on three targets in a Week 3 win for Buffalo.

Andy Borregales

PK

Borregales accounted for New England's scoring with 35- and 40-yard field goals but missed one from 38 yards in the third quarter. The second-year kicker has had a bit of a shaky start to the 2026 season, making just five of seven field-goal tries while going 3-for-3 on extra points. Kicking in an offense that is struggling to score points, Borregales isn't a recommended fantasy option ahead of next Sunday's date with the Bills.

Behren Morton

QB

Dametrious Crownover

OT

Leonard Taylor III

DT

A.J. Brown

WR

Kyles noted that Brown was wearing cleats, which could hint that he was able to do some on-field exercises. After being placed on injured reserve Sept. 12, Brown won't be eligible to start practicing with his teammates until Week 6, but the wideout at least seems to be making good progress in his recovery from the high-ankle sprain he sustained in the season-opening loss to the Seahawks.

Mack Hollins

WR

Hollins saw nearly twice as many targets as the next closest option DeMario Douglas (five), and his 87 yards were his highest total in a regular-season contest since Week 10 of the 2025 campaign. With A.J. Brown (ankle) on injured reserve, someone will have to take the reins as the Patriots' top option at wide receiver, and Hollins certainly showed he's capable of handling a larger workload.

Rhamondre Stevenson

RB

As was the case with backfield mate TreVeyon Henderson, Stevenson saw his opportunities on the ground capped to an extent by a game script that saw the Patriots already down 11 by halftime and 25 heading into the fourth quarter. Stevenson was just one carry and rushing yard apiece behind Henderson's workload on the ground, and both backs will look to be more involved in a key Week 4 road matchup against the Bills next Sunday.

TreVeyon Henderson

RB

Playing in his second game of the season, Henderson led the Patriots in carries and rushing yards, yet each of those figures were only one more than those generated by backfield mate Rhamondre Stevenson. Henderson had a much more efficient showing in his Week 2 season debut with a 16-carry, 76-yard, one-touchdown showing against the Steelers, but game script had a significant impact on the volume for both of the Patriots' backs Sunday. Henderson will look to get back on track in a key Week 4 road divisional matchup against the Bills next Sunday.

Jaylen Reed

S

Craig Woodson (shoulder) is inactive, so Reed will draw his first start of the season. Reed saw some playing time on defense during the Patriots' Week 2 win over the Steelers, with the second-year pro finishing with two tackles (one solo).

Quintayvious Hutchins

LB

Hutchins appeared in both of the Patriots' first two games of the 2026 campaign, accumulating three total tackles. The rookie will now miss at least four games while tending to a knee injury. While Hutchins has played sparingly, his absence will still allow Gabe Jacas and Jose Ramirez to see a little more action.

Dell Pettus

S

Pettus exited the second quarter of Sunday's 20-3 win over the Steelers with an ankle injury, and he'll now have to miss at least the next four games while on IR. With Craig Woodson (shoulder) also injured, the team will likely look to sign or elevate a player from the practice squad for Sunday's Week 3 matchup against the Jaguars.

Brenden Schooler

S

Schooler can now return to practice but won't be eligible to appear in a game until Week 5 due to being on the reserve/non-football injury list. Once officially activated, the 29-year-old should contribute as a depth defender.