San Francisco 49ers

Nick Bosa

DE

Bosa apparently still isn't ready for team drills, but he continues to trend in a positive direction as training camp rolls on, drawing praise from teammate Trent Williams, per Wagoner. When healthy, he figures to be the key to a San Francisco plan to fix a pass rush that was among the worst in the league in 2025.

Alfred Collins

DT

Collins was working through a shoulder injury during the offseason, but he's now healthy enough to participate in practices. The 2025 second-rounder played in 16 regular-season games in his rookie year, finishing with 17 tackles (four solo), including 1.0 sacks, two pass defenses, two forced fumbles and two fumble recoveries.

Trenton Irwin

WR

Both Ricky Pearsall (knee) and Christian Kirk (calf) are dealing with injuries, so the addition of Irwin gives the 49ers some added depth at wide receiver for training camp. Irwin spent the majority of the 2025 season on the Jets' practice squad after failing to make the Jaguars' 53-man roster at the end of training camp, and he's considered a longshot to crack San Francisco's roster for the 2026 campaign. He last saw regular-season action in 2024 with the Bengals, when he logged three catches (on 10 targets) for 15 yards across seven games.

Josiah Deguara

TE

Deguara was a third-round pick of the Packers in the 2020 NFL Draft and has played for three different franchises across his six-year career. He appeared in 12 regular-season games for the Cardinals in 2025, when he contributed mostly on special teams while logging three catches (on five targets) for 21 yards and a touchdown. Deguara gives the 49ers some extra depth at tight end while George Kittle continues to be sidelined by a torn right Achilles that he suffered in January.

Ji'Ayir Brown

S

Brown suffered a hamstring injury during San Francisco's win at Philadelphia in the wild-card round of the postseason back in January, but it seems like he's now back in football shape for training camp. He figures to again occupy one of the 49ers' starting spots at safety in 2026.

Ricky Pearsall

WR

Pearsall's injury has reportedly caused "concern" for the 49ers, per Nick Wagoner of ESPN, and the team is "exploring all options." As Barrows reports, surgery is being weighed among those options, though undergoing a procedure now could cost Pearsall the entire 2026 season. In the wake of Pearsall's ongoing evaluation, San Francisco signed veteran wideout Deebo Samuel to a one-year contract on Tuesday. Christian Kirk (calf) is also managing an injury that has hampered his ability to practice during the early stages of camp.

Deebo Samuel

WR

Samuel will return to San Francisco after spending the 2025 campaign with the Commanders, with whom he reeled in 72 of 99 targets for 727 yards and five touchdowns while also adding 75 yards and a score over 17 carries in 16 regular-season contests. The wide receiver spent the first six seasons of his NFL career in Kyle Shanahan's offense with the 49ers, and he likely will have no problem fitting right back in. The 49ers are concerned about the availability of Ricky Pearsall (knee) in 2026, while free-agent addition Christian Kirk is dealing with a calf injury early in training camp. The team added veteran Mike Evans in free agency, and he'll enter the 2026 campaign as the team's No. 1 wide receiver. After Evans, Samuel will compete with Pearsall (if available), Kirk and rookie second-round pick De'Zhaun Stribling for touches in the WR room.

Andrew Farmer II

DE

Farmer was not picked up by another squad after the 49ers waived him with an injury designation earlier in the week, and now he'll be required to stay on the team's IR list for the year unless he negotiates an injury settlement. He last played regular-season snaps in 2023 with the Chargers.

William Bradley-King

DE

Bradley-King wasn't claimed by another team after the 49ers waived him Wednesday, and now he'll have to spend the entire season on IR unless he negotiates an injury settlement with the club. His last regular-season snaps came in 2022 with Washington.

Mac Jones

QB

Jones was able to throw at George Kittle's (Achilles) Tight End University last week. The backup quarterback started eight regular-season games for the 49ers last year and will remain a key depth piece for the organization going into the 2026 season.

Malik Mustapha

S

Mustapha was the starting free safety for the 49ers in 2025 after returning from knee surgery, but he has been competing with Marques Sigle to keep the job. This setback will allow Sigle to show himself as a more consistent and productive option, so Mustapha will need to show out once he returns to the field.

Kaelon Black

RB

Black will look to make the most of his immediate opportunities at camp, with Vic Tafur of The Athletic noting that the rookie third-rounder had already gotten off to a strong start. While James should still be ready in advance of Week 1, his grasp on the No. 2 backfield role could lessen if Black is able to continue stringing together momentum. Isaac Guerendo (pectoral) also began training camp on the active/PUP list, leaving Patrick Taylor and Sincere McCormick as Black's main current competition for reps. Given these developments, Black's average fantasy draft position will figure to rise in advance of the preseason.

Jordan James

RB

It's a rough start to training camp for a player that some had tabbed as the favorite for San Francisco's No. 2 RB job. James should be ready well before Week 1, but missed practice time is a big deal for a player in his situation. The Niners currently have third-round pick Kaelon Black and veteran journeymen Patrick Taylor and Sincere McCormick for depth behind Christian McCaffrey.

Gracen Halton

DT

It's not the ideal start to Halton's pro career after he was drafted in the fourth round back in April. He'll have some catching up to do when he's back to full strength, and in his absence, rookie undrafted free agent James Thompson could see more focus as a depth option on the defensive line.

Vederian Lowe

OT

Lowe is expected to miss some time, and his availability for the start of the 2026 regular season may now be in question. Until he can return to the practice field, veteran Brandon Parker could get more attention as a backup option at tackle.

Nate Hobbs

CB

Hobbs missed the first day of camp with an unspecified illness, but he returned to the practice field Monday. It appears he has also recovered from the MCL tear he suffered Week 17 of last season, so he should have a real opportunity to make San Francisco's 53-man roster in a depth capacity.

Romello Height

DE

Height suffered an injury during Monday's training camp practice, and trainers appeared to be attending to both his arms and his right leg. The rookie third-round pick is competing to carve out a role at outside linebacker in Year 1 with the 49ers.

Christian Kirk

WR

Kirk walked off the field with trainers Sunday. Soft-tissue injuries are common during training camp, as players are ramping up to full speed and in pads after a long offseason. The severity of Kirk's calf strain isn't known, but consider him day-to-day. Kirk signed with the Niners in March and is expected to operate as the primary slot receiver alongside Mike Evans and Ricky Pearsall this season.

Jake Tonges

TE

Tonges appears back to full health after having suffered a plantar fascia injury during San Francisco's playoff loss to the Seahawks back in January. With George Kittle (Achilles) having been placed on the active/PUP list to start training camp, Tonges currently is positioned as the 49ers' top tight end. If Kittle's recovery lingers into the regular season, Tonges could kick off the 2026 campaign with a notable workload.

Kevin Givens

DT

Givens is set to return to San Francisco, where he has spent his entire seven-year career. The 29-year-old recorded two tackles (one solo) across five games last season and will spend the remainder of the summer competing for a roster spot.

Isaac Guerendo

RB

Guerendo is still recovering from a torn pectoral he suffered while lifting earlier in the offseason. While the 26-year-old will be unable to practice for now, he is expected to return at some point before the end of training camp.

Mykel Williams

DE

Williams is still working his way back from a torn ACL he suffered in November 2025 and will now be sidelined indefinitely. The 22-year-old can be activated at any time and is expected to serve as one of the team's starting outside linebackers during the upcoming campaign.

Brandon Aiyuk

WR

Aiyuk is not on the 49ers' 90-man roster as the team opened training camp Saturday. Injuries and off-field issues had Lynch publicly state in January that Aiyuk will never play for the 49ers again, though it's unclear when a move to remove the veteran wide receiver from the team's roster will actually take place. Aiyuk signed a four-year, $120 million contract with the 49ers in August of 2024 but hasn't seen regular-season action since Week 7 of the 2024 campaign after tearing the ACL and MCL in his right knee.

George Kittle

TE

Kittle continues to recover from a torn right Achilles that he suffered in the 49ers' NFC playoff win over the Eagles in January. The veteran tight end has been optimistic that he's ahead of schedule in his recovery and will be ready for Week 1 against the Rams on Sept. 10. By being placed on the active/PUP list, Kittle is eligible to participate in practice once he's fully recovered from his injury, but he'll be limited to side work for the time being. If Kittle ends up missing regular-season games, then Jake Tonges (foot) would be in line to serve as the 49ers' TE1.

Christian McCaffrey

RB

McCaffrey earned All-Pro honors while rushing 311 times for 1,202 yards and 10 touchdowns across 17 regular-season games in 2025, and also leading all running backs with a 102-924-7 receiving line (129 targets). Head coach Kyle Shanahan acknowledged back in spring that the team may alleviate McCaffrey's workload in 2026 in order to keep him fresh, a fair concern given that the 30-year-old handled a career-high 413 touches last year. McCaffrey himself has downplayed any workload concerns, and his versatility will help him remain a high-end fantasy producer even if any of Jordan James, Kaelon Black, Isaac Guerendo (pectoral), Patrick Taylor, Jordan Mims or Jermar Jefferson earn a larger role this year.