Arizona Cardinals

Isaiah Adams

G

Adams has been working through a knee injury since the end of training camp, and the issue was severe enough for him to miss all three practice sessions during Week 1 prep. Per Bo Brack of GoPHNX.com, Jon Gaines will start at right guard in Adams' absence.

Garrett Williams

CB

Williams was limited at practice all week as he continues to recover from the torn Achilles he suffered late last season, and he'll have to wait at least one more week to make his 2026 debut. In his stead, Kei'Trel Clark could see a small uptick in snaps.

Dadrion Taylor-Demerson

S

Taylor-Demerson missed practice Thursday and Friday after logging a limited session Wednesday, and he'll now have to spend Sunday on the sidelines. In his absence, 2025 seventh-rounder Kitan Crawford might get a couple more chances to rotate in on defense.

Blake Gillikin

P

Gillikin has been battling a groin injury for a few weeks, though his full participation in Wednesday's practice is a positive sign regarding his availability for the Week 1 meeting with the Chargers.

Jeremiyah Love

RB

Love initially suffered a high-ankle sprain during preseason Week 1, and after practicing in a limited fashion from Wednesday through Friday, he entered the weekend as questionable to suit up. Josh Weinfuss of ESPN.com reported Friday that Love was trending toward making his debut Sunday, and Rapoport's report indicates that the rookie third overall pick indeed will avoid the Cardinals' list of Week 1 inactives. Such a decision will become known about 90 minutes before a 4:25 p.m. ET kickoff, but considering his lack of activity over the last month, Love may well be eased into his first NFL action while working in tandem with fellow running back Tyler Allgeier.