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NFL · 2026 · AI Picks

San Francisco 49ers

Betting picks, ATS record, and odds analysis for San Francisco 49ers. Updated daily.

87.5%

Win%

7-1

Record

-0.2u

GODDS Units

W1

Streak

FormWWWWWWLW

GODDS Record on San Francisco 49ers

3W-3L · -0.2u

Win Rate

50%

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San Francisco 49ers Betting Trends

ATS Record

5-3

62.5% cover rate

Home

5-0

100% at home

Away

2-1

67% on road

Scoring

29.4

19.5 allowed

San Francisco 49ers Injury Report

Dre Greenlaw

LB

Greenlaw had eight tackles in Sunday's win over the Raiders. While he was limited Thursday, he has more time to get cleared to suit up versus the Cowboys in Week 10. If Greenlaw can't get on the field, Jaden Dugger and Garret Wallow are both in line for more snaps.

Questionable

Mike Evans

WR

Shanahan's comments signal the 49ers are taking an extra cautious approach with the veteran wideout in the hopes that he'll be available down the home stretch of the season. While Evans hasn't officially been ruled out for Sunday's game at Dallas, he isn't expected to suit up in Week 10, per Brooke Evans of the 49ers' official site. Until he's fully recovered and ready to go again, his absence should continue to open up additional opportunities outside for 2025 fourth-rounder Jordan Watkins.

Questionable

Deebo Samuel Sr.

WR

Samuel has managed back-to-back capped sessions to kick off Week 10 prep as he vies for his first game action since Week 5 at Seattle, when he injured his right hamstring. Friday's injury report will reveal his odds to suit up Sunday in Dallas.

Questionable

Jaden Dugger

LB

Dugger set the tone for the 49ers right out of halftime, when he intercepted a pass from Kirk Cousins intended for Tre Tucker and returned it 35 yards for a pick-six for the first defensive touchdown of Dugger's young NFL career. The rookie fifth-rounder has logged at least six solo tackles in three of his last four games and is up to 36 tackles (25 solo), including 1.0 sacks, and one pick-six through eight regular-season games.

Active

Trent Williams

OT

Williams presumably sustained a shoulder injury in Week 9 versus the Raiders, and now his availability for Week 10 is in some doubt. If he can't log a full practice Friday, there's a chance he could end up carrying an injury designation into the weekend.

Questionable

San Francisco 49ers Pick History

San Francisco 49ers Betting FAQ

What is the San Francisco 49ers record this season?+
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San Francisco 49ers Picks & Betting Analysis 2026

GODDS tracks every San Francisco 49ers bet with a public win-loss record. Our AI algorithm reads the San Francisco 49ers matchups it covers on signals such as season record, ATS history, recent form, scoring edge, line movement, injuries and head-to-head data, and publishes a pick only when its model gives a side 70% or more.

The San Francisco 49ers are 7-1 this season and covering the spread at a 62.5% rate. They average 29.4 points per game and allow 19.5.

The San Francisco 49ers play at Levi's Stadium in Santa Clara, CA in the NFC West Division. Founded in 1946.

For upcoming San Francisco 49ers games, see San Francisco 49ers team page. For today's full slate, see NFL picks today.

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