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Settings →NFL · 2025 · AI Picks
Betting picks, ATS record, and odds analysis for San Francisco 49ers. Updated daily.
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Sincere McCormick
RB
McCormick was dropped by San Francisco in late May, but the team has decided to bring him back into the fold. The 25-year-old's last in-game NFL action came with the Raiders in 2024, when he appeared in five contests and rushed 39 times for 183 yards while catching six of seven targets for 29 yards.
Mike Evans
WR
"I pinch myself every day," said teammate George Kittle, who then told reporters that Evans caught "three to five" TDs in a red-zone period. Dominance in unpadded practices doesn't mean much, especially for a player who already has such a strong track record, but it's a good sign that Evans is fitting in with the 49ers and earning praise from fellow future Hall of Famers like Kittle and LT Trent Williams. The 32-year-old wideout seems to have been a full participant throughout the voluntary offseason program, acclimating quickly to Kyle Shanahan's offense.
Mac Jones
QB
Jones said Wednesday that he would be ready for training camp in July, so it doesn't seem like there's any major cause for concern. He should be considered the favorite to land San Francisco's backup job behind Brock Purdy in 2026.
Brandon Aiyuk
WR
Aiyuk's warrant relates to a December video posted of himself driving nearby the 49ers' stadium. San Francisco GM John Lynch said back in January that Aiyuk will not play for the team again, while head coach Kyle Shanahan said in late March during the NFL owners' meeting that the team is in "no rush" to release the wideout and would prefer to receive some form of compensation via a trade. The 49ers inked veteran wideouts Mike Evans and Christian Kirk in free agency to join third-year pro Ricky Pearsall, as well as selecting rookie De'Zhaun Stribling in the second round of the 2026 NFL Draft at No. 33 overall. Aiyuk did not play in 2025 while rehabbing from ACL and MCL tears in his right knee that he sustained during the 2024 campaign, and he was placed on the reserve/left squad list last December.
George Kittle
TE
Kittle hedged his answer, saying he "has a chance" to be ready for the start of the regular season, but the veteran tight end has been open about the fact that he's targeting a Week 1 return, as have head coach Kyle Shanahan and GM John Lynch. Per Florito Maniego of NBC Sports Bay Area, Kittle said Monday that he's already resumed "running over 16 miles an hour," which is a notable step in his recovery an Achilles' tear initially suffered Jan. 11. Throughout spring practices and mandatory minicamp Kittle worked on the side and with trainers, but it's possible he could be ready to ramp up his activity level during training camp in July.
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GODDS will generate picks when San Francisco 49ers games are available.
View all NFL picks today →GODDS tracks every San Francisco 49ers bet with a public win-loss record. Our AI algorithm evaluates all San Francisco 49ers matchups using 18 signals — season record, ATS history, recent form, scoring edge, line movement, injuries, and head-to-head data.
The San Francisco 49ers play at Levi's Stadium in Santa Clara, CA in the NFC West Division. Founded in 1946.
For upcoming San Francisco 49ers games, see San Francisco 49ers team page. For today's full slate, see NFL picks today.
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